TBAF offers unique advantages in reaction systems. (Austin, TX) – June 5, 2008 – SACHEM has published a white paper titled “The Synthetic Utility of Tetrabutylammonium Fluoride” online.  SACHEM’s Tetrabutylammonium Fluoride (TBAF) trihydrate represents the potential for a dry source of fluoride and has unique base and non-nucleophilic properties in an organic reaction system. SACHEM provides the product in a trihydrate form, which is readily soluble in THF, a common medium.

Dr. Charles Little, Principal Scientist at SACHEM, says, “TBAF is well-known as a desilylating agent, but most people are unfamiliar with its many other uses in organic synthesis.  This white paper reveals that TBAF is a much more versatile reagent, using specific examples of reactions that highlight the unique basicity and nucleophilicity of this highly versatile compound.”  SACHEM is one of the leading providers of bulk quantity TBAF.
SACHEM, Inc. delivers highly pure, precise and innovative chemical solutions designed to solve the most demanding and challenging applications.  For over 50 years SACHEM has provided chemical solutions and services to customers in key markets including electronics, biotechnology, starch modification, polymers, catalysts, pharmaceutical and agricultural chemicals.  Based in Austin, Texas, SACHEM’s expanding worldwide operations include manufacturing and research facilities in North America, Europe and Asia with a global service network and presence spanning over 30 countries.