フッ化テトラブチルアンモニウム (TBAF)

SACHEMはフッ化テトラブチルアンモニウム (TBAF) を三水和物結晶として提供しています。それは下記の特徴を備えています。

  • 最低限の水分(TBAF各モルに対し水3モルのみ)
  • さまざまな反応システムにおける増大反応に関し、有機溶剤で簡単に溶解する。
  • 増大アクセシビリティに関し、フッ化物の「無水」のソース。
  • 塩基触媒反応における使用に関し、非求核塩基。
  • TBDMS(tert-ブチルジメチルシリル基)保護アルコールに関し、強力脱シリル剤。

アプリケーション:

TBAF製品のご購入:

当社施設間のネットワークとシームレスな流通サポートによって、世界中どこでも均一性、信頼性があるTBAFを分量にかかわらずご購入いただけます。

  • 一括大量購入の場合は、商業規模生産が可能。
  • TBAF 三水和物25 kg と50 kgファイバードラムのパッケージ

技術資料:
TBAFの合成的有用性  技術資料のダウンロード

ご購入可能な製品

フッ化テトラブチルアンモニウム (TBAF) 三水和物、 98%
CAS# 87749-50-6
SDS

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フッ化テトラブチルアンモニウに関して選択された記事と特許

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[toggle title=”Click here for selected articles and patents on tetrabutylammonium fluoride.”]

1. Adam, M. J.; Jivan, S.; Huser, J. M.; Lu, J. (2000).11C-methylations using 11C-methyl iodide and tetrabutylammonium fluoride. Radiochimica Acta (2000), 88(3-4), 207-209.

2. Bartsch, Richard (1970) . Eliminations from 2-butyl halides induced by halide ions in dimethylformamide and dimethyl sulfoxide. Journal of Organic Chemistry 35(4), 1023-5.

3. Crawley, Seth and Funk, Raymond. (2006). Generation of Aza-ortho-xylylenes via Ring Opening of 2-(2- Acylaminophenyl)aziridines: Application in the Construction of the Communesin Ring System. Organic Letters 8(18), 3995-3998.

4. Dahlstedt, Emma; Hellberg, Jonas; Petoral, Rodrigo M., Jr.; Uvdal, Kajsa (2004 Synthesis of tetrathiafulvalenes suitable for self-assembly applications. Journal of Materials Chemistry, 14(1), 81-85.

5. Denmark, Scott E; Pan, Weitao. (2003). Intramolecular Syn and Anti Hydrosilylation and Silicon-Assisted Cross-Coupling: Highly Regio- and Stereoselective Synthesis of Trisubstituted Allylic Alcohols.Organic Letters 5(7), 1119-1122.

6. Hojo, Makoto; Ishibashi, Naruyasu; Hosomi, Akira(1994). Heteroarylthiomethylsilanes. Synthesis and application to heteroarylthiomethylation of carbonyl compounds. Heteroatom Chemistry 5(3), 229-34.

7. Lyapkalo, Ilya M.; Webel, Matthias; Reissig, Hans-Ulrich (2001). Enantioselective synthesis of cyclohexenylalkenes by asymmetric deprotonation of 4-tert-butylcyclohexanone followed by O-nonaflation and Heck couplings. Synlett (8), 1293-1295.

8. Muratam Miki; Ohara, Hiroya; Oiwa, Ryo; Watanabe, Shinji; Masuda,Yuzuru (2006).Palladium(0)-catalyzed silylation of aryl halides with triorganosilanes: synthesis of aryl(2-furyl)silanes. Synthesis, (11), 1771-1774.

9. Ogawa, Toshihisa; Hatayama, Katsuo; Maeda, Hiroshi; Kita, Yasuyuki (1994). Mild and facile cleavage of 2-cyanoethyl ester using sodium sulfide or tetrabutylammonium fluoride. Synthesis of 1,4-dihydropyridine monocarboxylic acids and unsymmetrical 1,4-dihydropyridine dicarboxylates. Chemical Pharmaceutical Bulletin 42(8), 1579-89.

10. Ozasa, Nobuko; Wadamoto, Manabu; Ishihara, Kazuaki; Yamamoto, Hisashi (2003).Aldol synthesis with an aqueous solution of formalin. Synlett (14), 2219-2221.

11. Robins, Morris J.; Sarker, Sanchita; Samano, Vicente;.Wnuk, Stanislaw F (1997). Nucleic acid related compounds. 94. Remarkably high stereoselective reductions of 2′- and 3′-keto nucleosides to give arabino, ribo, and xylofuranosyl nucleosides with hydrogen isotopes at C2′ and C3′. Tetrahedron 53(2), 447-456.

12. Sahoo, Akhila K.; Oda, Takuro; Nakao, Yoshiaki; Hiyama, Tamejiro (2004). Cross-coupling of triallyl(aryl)silanes with aryl bromides and chlorides: An alternative convenient biaryl synthesis. Advanced Synthesis Catalysis 346(13-15), 1715-1727.

13. Shan, Daxian ; Zheng, Ailian; Ballard, C. Eric; Wang, Wei;. Borchardt, Ronald T; Wang, Binghe (2000). A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis. Chemical Pharmaceutical Bulletin (2000), 48(2), 238-244.

14. Sekine, Mitsuo; Yamada, Takeshi; Saneyoshi, Hisao; Seio, Kohji (2007). World Patent 2007/102581. Preparation of 2′-Hydroxyl-Modified Ribonucleoside Derivative. World Patent Office.

15. Sharma, G. V. M.; Reddy, V. Goverdhan; Chander, A. Subhash; Reddy, K. Ravinder (2002) Tetra-n-butylammonium fluoride: an efficient base for aza-Michael addition-synthesis of glycosyl b-amino acid esters. Tetrahedron: Asymmetry 13(1), 21-24.

16. Shiba, Yoshinobu (2007). World Patent 2007/099896. Method For Detaching Protecting Group On Nucleic Acid.  World Patent Office.

17. Stawinski, Jacek; Stroemberg, Roger; Thelin, Mats; Westman, Erik (1988). Studies on the t-butyldimethylsilyl group as 2′-O-protection in oligoribonucleotide synthesis via the H-phosphonate approach. Nucleic Acids Research 16(19), 9285-98.

18. Tejero, Ismael; Huertas, Imma; Gonzalez-Lafont, Angels; Lluch, Jose M.; Marquet, Jordi (2005). A Fast Radical Chain Mechanism in the Polyfluoroalkoxylation of Aromatics through NO2 Group Displacement. Mechanistic and Theoretical Studies. Journal of Organic Chemistry 70(5), 1718-1727.

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